Knee - If knee joint effusion present, consider aspiration and intra-articular corticosteroids e.g. Triamcinolone 40 mg
NSAID: Naproxen 250 - 500 mg po BID or Naproxen Sodium 220-550 mg po BID or Salsalate 1500 mg po BID
If GI risk factors may add omeprazole 20 mg po daily
If renal dz, no response, or age > 65, consider Tramadol 50 mg daily to QID, or Opiates: Acetaminophen/codeine 30 mg QID or Acetaminophen/hydrocodone 5 mg 1-2 tabs QID
If no response, consider change of NSAID Diclofenac 50 mg BID or EC Aspirin 650 mg TID or
COX 2 inhibitor
Celecoxib 200 mg daily
Knee – consider intra-articular
Synvisc(hylan GF 20)2 ml weekly
X 3 weeks
Prior Authorization Criteria
Pathway does not replace clinical judgment and should be modified as needed for individual patients. Page last revised
10/26/09.
Please send comments to: lefevrem@health.missouri.edu